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Gallsten

Gallsten, or gallstone, refers to a hard particle that forms in the gallbladder or biliary tract from components of bile. Most gallstones are cholesterol stones, though pigment stones made of calcium bilirubinate also occur. Many individuals with gallstones have no symptoms, and stones are often found incidentally during imaging for another condition.

Gallstones develop when the balance of bile components is disrupted. Factors that increase cholesterol saturation, promote

Symptoms arise primarily when stones obstruct bile flow. This can cause biliary colic—sudden, severe pain in

Diagnosis typically begins with abdominal ultrasound, which detects gallstones and signs of inflammation. Blood tests may

Treatment depends on symptoms and risk. Asymptomatic stones are often managed with no surgery. Symptomatic gallstones

gallbladder
stasis,
or
alter
bile
pigment
can
lead
to
stone
formation.
Risk
factors
include
obesity,
rapid
weight
loss,
pregnancy,
age,
female
sex,
certain
medications,
and
genetic
predisposition.
Pigment
stones
are
more
common
with
chronic
hemolysis
or
biliary
infections.
Stones
can
remain
in
the
gallbladder
or
migrate
into
the
bile
ducts.
the
right
upper
abdomen
that
may
radiate
to
the
back
or
shoulder,
often
lasting
from
15
minutes
to
several
hours.
Nausea,
vomiting,
and
intolerance
to
fatty
meals
may
accompany
the
pain.
If
a
bile
duct
is
obstructed,
jaundice
or
fever
may
occur,
and
complications
such
as
acute
cholecystitis,
cholangitis,
or
pancreatitis
can
develop.
show
elevated
liver
enzymes
or
bilirubin
if
ducts
are
blocked.
In
some
cases,
magnetic
resonance
cholangiopancreatography
(MRCP)
or
endoscopic
procedures
are
used
to
assess
the
biliary
tree.
are
commonly
treated
with
cholecystectomy,
usually
by
laparoscopy.
Stones
in
the
bile
ducts
may
require
endoscopic
removal
via
ERCP.
Medical
dissolution
with
ursodeoxycholic
acid
is
an
option
for
selected
cholesterol
stones
when
surgery
is
not
feasible.
Prevention
focuses
on
risk
factor
modification,
though
stone
formation
can
still
occur
after
treatment.