Biurams

Biurams, also known as bioresorbable vascular scaffolds (BVS), are medical devices used in the treatment of coronary artery disease. They are designed to temporarily support blood vessels and gradually dissolve over time, leaving no permanent implant behind. This innovative technology aims to combine the benefits of drug-eluting stents with the natural healing process of the blood vessel.

The primary material used in biurams is a bioresorbable polymer, often polylactic acid (PLA), which is gradually broken down and absorbed by the body through natural metabolic processes. This absorption process typically takes about 2 to 3 years, during which the scaffold provides mechanical support to the artery and elutes drugs to prevent restenosis, the re-narrowing of the artery.

The concept behind biurams is to restore vessel functionality and allow for the natural healing process without leaving a permanent metallic stent in place. This can potentially reduce long-term complications such as late stent thrombosis and allow for the restoration of vasomotion, the natural ability of blood vessels to constrict and dilate.

Clinical studies have shown promising results with biurams, demonstrating their efficacy in treating coronary artery disease. However, the use of biurams also comes with challenges, including the need for precise implantation techniques and careful patient selection to ensure optimal outcomes. Ongoing research and technological advancements continue to refine the design and application of biurams, aiming to improve their safety and effectiveness in clinical practice.