zwitterionbased
Zwitterionbased refers to materials, polymers, and coatings that incorporate zwitterionic moieties—functional groups containing both positive and negative charges within a single molecule. The zwitterionic unit imparts overall neutrality and a strong hydration shell, influencing surface interactions and stability in aqueous environments.
Zwitterionbased systems typically exhibit high hydrophilicity and low nonspecific protein adsorption, contributing to antifouling properties and
Design and synthesis rely on zwitterionic monomers such as carboxybetaine and sulfobetaine derivatives (e.g., CBMA, SBMA).
Applications include antifouling coatings for medical devices and ships, biocompatible hydrogels for tissue engineering, and drug
Challenges include synthesis cost, scalable production, and stability under varying pH and ionic strength. Long-term performance