täitedosale

Täitedosale is an Estonian term that translates to "filling dose" or "supplementary dose" in English. It refers to a dose of medication administered in addition to a primary or initial dose. This concept is often employed in medical treatments to ensure the therapeutic level of a drug is maintained in the body over time, especially when the drug has a short half-life or is eliminated rapidly.

The rationale behind a täitedosale is to prevent a drop in drug concentration below the minimum effective concentration, which could lead to a relapse of symptoms or a decrease in treatment efficacy. These supplementary doses can be given at specific intervals, such as every few hours or daily, depending on the drug's pharmacokinetic properties and the patient's condition.

In some contexts, täitedosale might also refer to a dose given to compensate for factors like poor absorption, increased metabolism, or drug interactions that might reduce the effectiveness of the initial dose. The specific timing and amount of a täitedosale are determined by healthcare professionals based on clinical guidelines and individual patient assessment. This approach is common in various fields of medicine, including anesthesiology, emergency medicine, and chronic disease management.