twicedaily

Twice-daily generally refers to a frequency of two events per day, roughly every 12 hours. The term may be written as twice daily, twice-daily, or bid in shorthand, and it contrasts with once daily or three times daily.

In medical contexts, twice-daily dosing indicates the amount of medicine should be taken twice within a 24-hour period, commonly distributed roughly 12 hours apart. Prescriptions may specify exact times and may depend on the drug's pharmacokinetics and patient factors. In skincare or personal care, "twice daily" commonly appears on product directions, such as cleansers or moisturizers, advising use morning and night.

Adherence, the drug's half-life, and potential interactions influence whether twice-daily dosing is appropriate or safe. Some medications are prescribed more or less frequently; others support flexible timing.

Examples include medications for chronic conditions, where consistent exposure is important; topical agents on the skin; dietary supplements. However, dosing regimens should be followed as prescribed and clarified with a healthcare provider.

Ambiguity arises when schedules are not specified or the exact times are unclear; patients should confirm times with their providers to ensure appropriate administration.

See also dosing schedule, frequency, q12h, bid.