rosuvastatin

Rosuvastatin, commonly known by the brand name Crestor, is a statin medication used to treat high cholesterol and related conditions. It belongs to a class of drugs that function as HMG-CoA reductase inhibitors. Its primary purpose is to lower levels of low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol, in the blood. By doing so, it helps reduce the risk of cardiovascular events such as heart attacks and strokes in at-risk individuals.

The medication works by blocking the HMG-CoA reductase enzyme in the liver, which is responsible for producing cholesterol. In addition to lowering LDL, rosuvastatin can modestly reduce triglycerides and increase high-density lipoprotein (HDL) cholesterol, the "good" cholesterol. It is typically prescribed for once-daily oral administration and is most effective when combined with lifestyle modifications like diet and exercise.

Common side effects include muscle pain, headache, and nausea. While rare, more serious adverse effects such as myopathy (muscle weakness) or rhabdomyolysis, a severe breakdown of muscle tissue, can occur. Liver function may also be affected, so periodic monitoring is often recommended. Rosuvastatin is considered a first-line treatment for managing hyperlipidemia and preventing cardiovascular disease.