microglandulaires

Microglandulaires is a descriptive term used in histopathology to denote a pattern in which numerous small glands predominate within a tissue. It is not a single disease but a pattern that can be seen in various organs and in both benign and neoplastic processes. The label highlights the size and arrangement of the glands rather than a specific diagnosis, and its clinical significance depends on the broader histologic context.

The term is most commonly encountered in discussions of glandular or epithelial proliferations, including lesions of the breast and other glandular tissues. In breast pathology, for example, a microglandular pattern may be observed in certain benign proliferations as well as in neoplastic conditions. Because microglandular formations can mimic malignant features, accurate interpretation relies on careful histologic assessment and, when appropriate, adjunct immunohistochemical studies to distinguish benign processes from carcinoma.

Diagnosis hinges on tissue architecture and cellular characteristics, with pathologists evaluating gland size, mucin content, cytologic uniformity, and the presence or absence of surrounding myoepithelial cells. The distinction between a benign microglandular proliferation, a premalignant lesion, or an overt malignancy guides management decisions.

Management and prognosis are determined by the underlying diagnosis rather than the microglandular pattern alone. Benign microglandular proliferations typically require limited intervention and follow-up, while lesions with malignant potential or associated carcinomas necessitate oncologic assessment and treatment.

In summary, microglandulaires describes a histological pattern of small glands that can appear in diverse conditions, underscoring the importance of contextual histopathology for accurate diagnosis and management.