lääkejakautuminen
Lääkejakautuminen refers to the process by which a drug distributes throughout the body's various tissues and fluids after administration. Once a drug enters the bloodstream, it can move to different parts of the body, such as organs, fat tissue, and even across the blood-brain barrier. This distribution is influenced by several factors, including blood flow to different tissues, the drug's ability to cross cell membranes, its binding to plasma proteins and tissue components, and the physicochemical properties of the drug itself, such as its lipid solubility and ionization state.
The extent to which a drug distributes into different compartments of the body is often quantified by
Understanding lääkejakautuminen is crucial for determining appropriate drug dosages and predicting therapeutic effects and potential toxicity.