lipohypertrophia

Lipohypertrophia, also known as lipohyperplasia, is a condition characterized by the abnormal enlargement of adipose tissue, leading to an increase in body fat. This condition is distinct from obesity, as it is not caused by an excess of caloric intake or a sedentary lifestyle. Instead, lipohypertrophia is often associated with certain medical conditions, medications, or genetic factors.

One of the most common causes of lipohypertrophia is the use of certain medications, such as corticosteroids, which can lead to the accumulation of fat in various parts of the body. Other medical conditions that can result in lipohypertrophia include hypothyroidism, Cushing syndrome, and certain types of cancer. Genetic factors, such as mutations in the leptin receptor gene, can also predispose individuals to lipohypertrophia.

The clinical presentation of lipohypertrophia varies depending on the underlying cause and the distribution of fat deposits. Common symptoms include localized fat deposits, such as a moon face or buffalo hump, as well as generalized fat accumulation. In some cases, lipohypertrophia can lead to complications, such as insulin resistance, hypertension, and dyslipidemia.

The diagnosis of lipohypertrophia typically involves a physical examination, medical history, and laboratory tests to identify the underlying cause. Treatment options depend on the underlying condition and may include lifestyle modifications, medication adjustments, or medical interventions to address the underlying cause. In some cases, surgical procedures may be necessary to remove excess fat deposits.