lipofiilsusele
Lipofiilsusele, also known as lipofuscin accumulation, refers to the age-related buildup of a pigmented pigment granule known as lipofuscin within cells. Lipofuscin is composed of lipid-containing residues of lysosomal digestion, often considered an inert waste product. It predominantly accumulates in long-lived post-mitotic cells such as neurons, cardiac myocytes, and liver cells.
This accumulation is associated with cellular aging and oxidative stress, as it results from the incomplete
In biological tissues, excessive lipofuscin deposits can interfere with normal cell function, potentially contributing to age-related
Detection of lipofuscin is commonly achieved through histological staining techniques or fluorescence microscopy. Its accumulation has
Overall, lipofuscin accumulation is a natural aspect of cellular aging, reflecting the long-term wear and oxidative