hyperglykeemisiin

Hyperglykeemisiin is not a standard term in medical literature. It resembles Finnish formations related to glycemia and may be used to denote abnormal glycemic states. The expression could reflect either a misspelling of hyperglycemia (high blood glucose) or, less commonly, a reference to glycine metabolism disorders such as nonketotic hyperglycinemia. Because the term is not widely established, sources should specify its intended meaning.

If interpreted as hyperglycemia, the term would describe persistently elevated blood glucose. Common causes include diabetes mellitus, acute illness, stress, pancreatopathy, or certain medications. Symptoms often include excessive thirst, frequent urination, fatigue, and blurry vision. Diagnosis relies on fasting plasma glucose, random glucose tests, HbA1c, or an oral glucose tolerance test. Treatment focuses on lowering glucose levels through lifestyle changes and medications (for example metformin, insulin, or other antidiabetic drugs), along with managing underlying conditions and preventing complications.

If read as hyperglycinemia (nonketotic hyperglycinemia), it describes elevated glycine due to defects in the glycine cleavage system. It typically presents in infancy with hypotonia, lethargy, apnea, and seizures. Diagnosis uses amino acid analysis showing elevated glycine in CSF and plasma and an increased CSF/plasma glycine ratio, supported by genetic testing of GLDC, AMT, or GCSH. Treatment is supportive and may include sodium benzoate to reduce glycine, a low-glycine diet, and NMDA receptor antagonists such as dextromethorphan; prognosis varies with severity.

In medical writing, the term is uncommon; clarification is recommended when encountered.