homothorax

Homothorax is a rare congenital anomaly characterized by the presence of pleural effusion, a significant amount of fluid accumulation in the pleural space, in the absence of any identifiable underlying cause such as heart failure, infection, or malignancy. This condition is typically diagnosed in neonates and infants and is believed to result from impaired lymphatic drainage from the pleural space. The fluid is often chylous, meaning it contains lymph and digested fats, suggesting a lymphatic origin.

The clinical presentation of homothorax can vary. Some infants may be asymptomatic, while others may exhibit respiratory distress, tachypnea, or cyanosis due to the compression of the lungs by the effusion. Diagnosis is usually made through imaging studies such as chest X-ray or ultrasound, which reveal the pleural effusion. Thoracentesis, the removal of pleural fluid, is crucial for diagnosis. Analysis of the pleural fluid confirms the presence of chylothorax if high levels of triglycerides and lymphocytes are detected.

Treatment for homothorax primarily involves managing the effusion and addressing any resulting respiratory compromise. Repeated thoracentesis may be performed to relieve pressure and improve breathing. In persistent or severe cases, surgical intervention, such as pleurodesis or ligation of abnormal lymphatic vessels, may be considered. The long-term prognosis for homothorax is generally good with appropriate management, though some infants may experience recurrent effusions.