hemolyzed

Hemolyzed refers to the condition or state in which red blood cells (erythrocytes) have undergone destruction or rupture, releasing their cellular contents into the surrounding fluid. This process can occur naturally within the body or as a result of external factors, such as medical procedures or sample handling.

In a clinical context, hemolysis is an important consideration in the interpretation of blood test results. Hemolyzed blood samples can interfere with laboratory assays, leading to inaccurate measurements of analytes such as hemoglobin, potassium, and other intracellular substances. The presence of hemolysis in a blood sample is often visually indicated by a pink to red coloration of plasma or serum, signifying the release of hemoglobin from lysed red blood cells.

Hemolysis can occur due to various causes, including mechanical trauma during blood draw, improper sample handling, contamination, or pathological conditions such as hemolytic anemia, certain infections, or reactions to blood transfusions. It can also result from extensive in vivo destruction of red cells due to immune or enzymatic mechanisms.

Preventing hemolysis is a key aspect of proper phlebotomy procedures and sample collection, involving gentle handling, correct needle gauge, and prompt processing of samples. When hemolysis is present in a blood specimen, laboratories often note this in reports and may request a repeat sample to ensure accurate diagnostics.

In summary, hemolyzed refers to the breakdown of red blood cells, which has implications in both physiology and clinical diagnostics. Recognizing and managing hemolysis are essential for accurate laboratory testing and proper patient care.