gammaHCH

gamma-Hexachlorocyclohexane, commonly known as lindane, is one of the isomers of hexachlorocyclohexane (HCH), an organochlorine compound. The gamma isomer has the chemical formula C6H6Cl6 and is the isomer historically marketed and used as lindane. It is typically produced as part of technical HCH mixtures, which contain several isomers, including alpha- and beta-HCH.

Uses and production: Lindane has been employed as a broad-spectrum insecticide for agricultural crops, stored products, and wood treatment. It has also been used in the past as a pharmaceutical treatment for head lice and scabies, but such medical uses have become restricted or banned in many countries due to safety concerns. Environmental and regulatory considerations have led to a decline in its production and use in many regions.

Properties and health concerns: gamma-HCH is a lipophilic, persistent organic pollutant with low water solubility that tends to partition into fatty tissues and degrade slowly in the environment. It is neurotoxic to insects and can pose health risks to humans and wildlife through exposure, particularly with long-term or high-dose contact. Because of its persistence and potential for bioaccumulation, lindane is subject to regulatory controls in many jurisdictions.

Regulatory status: Lindane is listed under international environmental agreements as a persistent organic pollutant, and many countries have phased out or banned its use while permitting restricted exemptions in specific cases, such as vector control in malaria-endemic areas under strict conditions.