fibronectincoated
Fibronectin-coated refers to a material surface, scaffold, or device that has a layer of fibronectin applied to its exterior to create a biologically active interface that promotes cell adhesion, spreading, and signaling. Fibronectin is a high‑molecular‑weight extracellular matrix glycoprotein that exists in soluble plasma form and insoluble cellular matrix form. It interacts with cell surface receptors, particularly integrins, through motifs such as RGD (arginine–glycine–aspartic acid) and also binds to collagen and heparin, helping to organize the ECM and transmit mechanical cues to cells.
Coating methods typically involve passive adsorption of fibronectin from solution onto surfaces such as tissue culture
Applications of fibronectin-coated materials include standard cell culture to promote attachment and spreading, studies of cell