biarylbinding
Biarylbinding is a term used to describe noncovalent association between biaryl fragments, such as two aryl rings connected by a central biaryl bond. It covers both intramolecular interactions within a single molecule and intermolecular interactions between separate species. Biaryl moieties frequently engage in aryl-aryl contacts that contribute to binding, self-assembly, and molecular recognition in diverse chemical contexts.
The binding mode can be face-to-face, edge-to-face, or offset, and is influenced by factors such as substituents,
Quantification typically uses binding constants (Ka or Kd) and thermodynamic data from techniques like isothermal titration
Applications of biarylbinding appear in supramolecular chemistry and materials science, including self-assembling polymers, foldamers, and molecular