antiseborrheic

Antiseborrheic refers to substances used in dermatology to treat seborrheic conditions by reducing sebum overproduction and improving abnormal keratinization. The term is most often applied to therapies for seborrheic dermatitis and dandruff, conditions characterized by oily scalp or skin with flaking, redness, and irritation. Antiseborrheic products aim to control oiliness, curb fungal factors, and normalize the skin's turnover processes.

Many antiseborrheics act against Malassezia species, yeasts implicated in seborrheic disease, and also exert effects on keratinization or sebum dynamics. Common classes include antifungal agents such as ketoconazole, ciclopirox, zinc pyrithione, and selenium sulfide; and keratolytic or sebostatic substances such as salicylic acid, sulfur, and coal tar. The choice of agent depends on the site, severity, and tolerance.

Applications are most frequent in scalp care, delivered as shampoos or topical solutions, but antiseborrheics are also used on the face, chest, and other oily areas. Treatment regimens may require regular use to prevent relapse. Potential drawbacks include scalp irritation, dermatitis, odor or staining (notably with selenium sulfide or coal tar), and photosensitivity with certain agents.

Antiseborrheic therapy is often part of a broader management plan for seborrheic dermatitis and dandruff, sometimes in combination with anti-inflammatory or antifungal agents. As with all dermatologic treatments, efficacy varies among individuals, and long-term use should be guided by a clinician.