Verfestigungsverlauf
Verfestigungsverlauf is a medical descriptor used to describe how tissue changes become denser and harder over time. It is not a disease itself but a way to characterize the evolution of a process such as inflammation, fibrosis, calcification, or desmoplastic reaction around a lesion.
The term is commonly used in radiology and pathology to document progression or stabilization of an abnormality.
Assessment relies on serial imaging—computed tomography, magnetic resonance imaging, or ultrasound—to track changes in density, signal
Clinically, the Verfestigungsverlauf informs prognosis and management by indicating chronicity, response to therapy, or progression. A
Examples include pulmonary fibrosis after infection or inflammation, progressive liver cirrhosis with architectural changes, desmoplastic stroma