Thalidomides
Thalidomides refer to a family of chemical compounds derived from thalidomide, including the parent molecule and related analogs used in medicine. These compounds are chiral, and thalidide products are typically used as racemates or as specific enantiomeric formulations; enantiomers may interconvert in the body, which has implications for both efficacy and safety.
History and regulation have shaped the modern use of thalidomides. Thalidomide was introduced in the late 1950s
Pharmacology and mechanism are complex and continue to be studied. Thalidomide exhibits anti-inflammatory and anti-angiogenic effects,
Clinical use and derivatives have evolved. Thalidomides and certain analogs are used for conditions such as
Safety and regulation remain central. Products containing thalidomide are typically distributed under strict risk-evaluation and mitigation