TelomeretoTelomereProjekt
TelomeretoTelomereProjekt (TTTP) is an international collaborative research initiative focused on the biology of telomeres, the protective caps at chromosome ends. The project aims to advance understanding of telomere structure, length dynamics, and maintenance mechanisms across tissues and species, with the ultimate goal of informing aging research, cancer biology, and genome stability.
The concept envisions a coordinated effort to map telomere architecture from one end of a chromosome to
Core objectives include characterizing telomere length distribution and sequence composition in diverse cell types; elucidating the
Methods employed include long-read and ultra-long sequencing, single-molecule and single-cell assays, chromatin profiling, CRISPR-based functional screens,
Governance is organized as an international consortium with a steering committee, standardized data standards, and an
Expected outcomes include high-resolution telomere datasets, methodological benchmarks, and insights that could inform therapeutic strategies targeting