Plateauvaihe
Plateauvaihe, also called the plateau phase, is a stage in a cell growth curve during which cell proliferation slows or stops, and the total cell number stabilizes. It follows the exponential or log phase and precedes the decline or death phase. In this phase, net growth is near zero, even though cells may remain viable, and cultures can appear crowded.
Causes of the plateau phase include nutrient depletion, accumulation of waste products, depletion of oxygen or
Characteristics of plateauvaihe vary by organism and culture system. Specific growth rate approaches zero; cells may
Implications for research and industry include altered metabolism, gene expression, and responses to drugs or inhibitors,
Management and optimization strategies involve subculturing or passaging to fresh medium, adjusting inoculum density or feeding