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Neuroparalysis

Neuroparalysis refers to loss of motor function resulting from impairment of the nervous system. It encompasses paralysis caused by disease or injury affecting the brain, spinal cord, peripheral nerves, or the neuromuscular junction. Depending on the site of disruption, neuroparalysis may present as flaccid or spastic weakness, with limited or absent voluntary movement and varying degrees of muscle tone. Sensory changes may accompany motor loss, and autonomic symptoms can occur in some conditions.

Causes include central nervous system events such as stroke, traumatic brain injury, spinal cord injury, tumors,

Diagnosis relies on clinical assessment supplemented by imaging (MRI, CT), electrophysiology (nerve conduction studies, EMG), and

Management targets the underlying cause and functional rehabilitation. Acute care may require stabilization, airway protection, and

Prognosis is variable and depends on etiology, extent of neural involvement, and promptness of treatment. Some

or
demyelinating
diseases;
peripheral
nerve
injuries
from
trauma
or
compression;
polyneuropathies
from
diabetes,
infections,
autoimmune
disorders;
neuromuscular
junction
disorders;
toxic
or
metabolic
disorders;
and
congenital
conditions
affecting
motor
pathways.
Acute
onset
may
follow
accident
or
infection;
chronic
neuroparalysis
may
reflect
progressive
neurodegenerative
or
inflammatory
disease.
laboratory
tests
to
identify
inflammation,
infection,
metabolic
factors,
or
autoimmune
processes.
In
selected
cases,
lumbar
puncture
or
nerve
biopsy
is
used.
prevention
of
secondary
injury.
Rehabilitation
includes
physical
and
occupational
therapy;
assistive
devices
and
mobility
aids.
Pharmacologic
treatment
addresses
pain
or
spasticity;
disease-modifying
therapies
or
immunotherapies
may
be
used
for
autoimmune
conditions;
surgical
repair
or
decompression
can
be
indicated
for
certain
nerve
injuries;
prevention
of
complications
is
essential.
patients
regain
significant
function,
while
others
experience
lasting
paralysis.
Ongoing
research
in
neurorehabilitation
and
nerve
regeneration
seeks
to
improve
functional
outcomes.