Ledipasvir
Ledipasvir is a direct-acting antiviral medication used in combination with sofosbuvir for the treatment of chronic hepatitis C virus (HCV) infection. It is an NS5A inhibitor that interferes with viral RNA replication and assembly, and is typically given as part of a single-tablet regimen taken once daily.
Indications and regimen: Ledipasvir/sofosbuvir (90 mg/400 mg) is approved for adults with chronic HCV infection due
Administration and interactions: The tablet can be taken with or without food. Acid-reducing agents can lower
Adverse effects and considerations: Common adverse effects include fatigue, headache, nausea, and diarrhea. Serious liver-related or