Korkeaannos

Korkeaannos is a Finnish term used to refer to a dose amount that is higher than standard or recommended. The term is formed from korkea meaning high and annos meaning dose or portion. It is commonly encountered in medical and scientific texts, and may be written korkea-annos or korkeaannos, depending on stylistic conventions.

In clinical medicine, korkeaannos describes high-dose regimens such as korkea-annos chemotherapy or high-dose antimicrobial therapy. It is also used in radiation therapy and toxicology to indicate high levels of exposure. In nutrition or supplement contexts, a korkeaannos may refer to taking unusually large amounts of vitamins or minerals, which can carry risk of toxicity.

Considerations: High-dose approaches aim to achieve a stronger therapeutic effect but often increase the risk of adverse events, requiring careful patient selection, dosing calculations, and monitoring of organ function and blood tests. Dosing recommendations are defined in guidelines and drug labels, and deviations are managed by healthcare professionals.

Korkeaannos is therefore a descriptive term rather than a treatment modality itself, used to flag dosage levels that exceed standard practice and that demand appropriate medical oversight and risk assessment.