H2blockerare
H2blockerare is a class of medicines that reduce gastric acid production by competitively blocking histamine H2
Mechanism of action and pharmacology: H2blockerare are reversible antagonists of the histamine H2 receptor. Their effect
Common agents: The best known members are famotidine, ranitidine, cimetidine, and nizatidine. Ranitidine has been withdrawn
Indications and use: H2blockerare are employed for short- and intermediate-term management of ulcers and GERD, relief
Safety and side effects: Most people tolerate them well. Common adverse effects include headache, dizziness, constipation
History: H2blockerare were introduced in the 1970s as the first targeted gastric acid–suppressing therapy. They have