GPATs

GPATs may refer to two distinct concepts in science and education. In biochemistry, GPAT stands for glycerol-3-phosphate acyltransferases, a family of enzymes that catalyze the first step in glycerolipid biosynthesis. They transfer an acyl group from acyl-CoA to glycerol-3-phosphate, producing lysophosphatidic acid, a precursor for phosphatidic acid, diacylglycerol, triacylglycerol and various phospholipids. In mammals, several GPAT isoforms have been described (commonly GPAT1–4), with differences in subcellular localization and tissue distribution. GPAT activity is influenced by cellular energy status, substrate availability, and regulatory factors, and it plays a key role in lipid metabolism. Dysregulation of GPAT activity is studied in relation to metabolic conditions such as obesity, insulin resistance and fatty liver in model systems. In microbes and yeast, GPAT homologs contribute to lipid biosynthesis and membrane formation. The enzyme family is of interest for understanding metabolic regulation and as potential targets for modulating lipid synthesis.

GPAT also stands for the Graduate Pharmacy Aptitude Test, a national-level entrance examination in India for admission to Master of Pharmacy programs. The test is used by participating universities and institutes to select candidates for M.Pharm admission and, in some cases, for scholarships or fellowships. It assesses knowledge across pharmaceutical sciences, including pharmacology, pharmaceutics, medicinal chemistry and related disciplines. Eligibility generally requires a recognized Bachelor of Pharmacy degree. Successful performance enables admission to postgraduate programs in pharmacy across many public and private institutions.