Fluorideretentie

Fluorideretentie refers to the process by which fluoride ions are retained or accumulated within the body. This primarily occurs in calcified tissues, such as bones and teeth, where fluoride can incorporate into the hydroxyapatite crystal structure, forming fluorapatite. This substitution increases the resistance of tooth enamel to acid demineralization, a key mechanism in preventing dental caries.

The amount of fluoride retained by the body depends on several factors, including the dose and frequency of fluoride exposure, the duration of exposure, and individual physiological characteristics. Ingestion of fluoride from sources like fluoridated water, toothpaste, or supplements leads to systemic absorption. A significant portion of this absorbed fluoride is then taken up by the developing teeth and bones.

While fluoride retention in teeth is beneficial for caries prevention, excessive retention in bones can lead to skeletal fluorosis, a condition characterized by increased bone density and potential joint pain, particularly in areas with very high natural fluoride levels in drinking water over extended periods. The understanding of fluorideretentie is crucial in public health strategies related to optimal fluoride levels for dental health.