Endediastolisk

Endediastolisk is an adjective used in cardiology to describe anything pertaining to end-diastole, the final phase of the heart’s diastolic filling when the ventricles are filled with blood just before the onset of systole. In medical literature it most often appears in the context of end-diastolic measurements and states.

In physiology and clinical practice, the key end-diastolic concepts are end-diastolic volume (EDV) and end-diastolic pressure (EDP). EDV is the volume of blood present in a ventricle at the end of diastole, while EDP is the corresponding pressure. The amount of blood contained at end-diastole influences the stroke volume through the Frank–Starling mechanism, so changes in endediastolisk parameters reflect the heart’s filling status and preload.

Assessment of endediastolisk parameters is carried out using imaging and invasive methods. Echocardiography, including 2D and Doppler approaches, estimates left ventricular end-diastolic volume and related filling pressures; magnetic resonance imaging (MRI) and computed tomography (CT) can also quantify EDV. Invasive measurement via cardiac catheterization provides direct EDP. Normal values vary with body size and age; in an average adult, left ventricular EDV is roughly 110–130 mL, and resting EDP is typically around 5–12 mmHg, with variations depending on hydration status and cardiovascular conditions.

Clinically, abnormal endediastolisk findings indicate diastolic dysfunction or volume overload. Elevated EDV or EDP can accompany heart failure with preserved ejection fraction, valvular disease, or fluid overload, while reduced end-diastolic filling can occur with poor ventricular compliance or constrictive physiology.

Etymology and usage: the term is more commonly encountered in Swedish medical literature, where it describes end-diastolic phenomena. In English, the preferred term is typically "end-diastolic."