Diastolisk

Diastolisk is a term used in medical contexts to describe things related to diastole, the phase of the cardiac cycle when the heart muscle relaxes and the chambers fill with blood. Diastole contrasts with systole, the phase of contraction during which the heart pumps blood out of the chambers. During diastole, the ventricles relax, pressure falls, and atrial blood flow contributes to ventricular filling. The heart’s coronary arteries primarily receive blood during diastole.

In clinical practice, diastolic function is assessed to evaluate the heart’s ability to relax and fill. Diastolic dysfunction occurs when relaxation is impaired, which can increase filling pressures and contribute to symptoms of heart failure with preserved ejection fraction (HFpEF). Diastolic metrics are often measured with echocardiography, including transmitral E and A wave velocities, tissue Doppler e', and the E/e' ratio, as well as left atrial size and left ventricular filling pressures.

Diastolic blood pressure is the arterial pressure during diastole and is one component of the commonly reported systolic/diastolic blood pressure pair. Abnormal diastolic function can be caused by aging, hypertension, ischemic heart disease, obesity, diabetes, and valvular disease. Management focuses on controlling blood pressure and other contributing conditions, lifestyle modification, and, when appropriate, medications that address neurohormonal activation and volume status.

In English, the term aligns with diastolic or diastolic-related concepts; in Scandinavian languages, diastolisk is used as an adjective denoting the same idea.