Dermabond

Dermabond is a brand of topical tissue adhesive used to close skin wounds. It contains a cyanoacrylate compound (2-octyl cyanoacrylate) that rapidly polymerizes on contact with moisture in the skin, forming a flexible, protective bond that seals the wound edges and helps prevent bacterial intrusion.

Dermabond is intended as an alternative to sutures or staples for small, clean, well-approximated skin lacerations. It is often considered for facial wounds or other areas where cosmetic outcome is a priority. It is not recommended for contaminated or infected wounds, wounds under significant tension, deep wounds, or wounds over joints or mucous membranes (such as inside the mouth or around the eyelids). It should be used by trained healthcare professionals in appropriate clinical settings.

Application generally involves cleaning and drying the wound, then applying a thin layer of adhesive along the wound edge or bridging the edges with a light squeeze to ensure contact. The edges are held together briefly to allow bonding. The surrounding skin should be kept dry during the initial setting period. No routine removal of the adhesive is required; the bond gradually sloughs as the skin heals.

Safety considerations include the potential for mild skin irritation or contact dermatitis in some individuals, and, rarely, allergic reactions to cyanoacrylates. Adverse outcomes such as infection or wound dehiscence can occur if the product is used on unsuitable wounds or if aftercare instructions are not followed.

Dermabond is used as a modern alternative to traditional closure methods in suitable cases, contributing to faster wound closure and convenient aftercare in many clinical settings.