Denanderie

Denanderie refers to the practice of removing or avoiding the use of androgens, a group of hormones that include testosterone and dihydrotestosterone. This term is often discussed in the context of gender-affirming care, particularly for transgender women or individuals who experience gender dysphoria associated with elevated androgen levels. Androgen suppression is typically achieved through medical interventions such as hormone replacement therapy (HRT), which may involve the use of medications like estrogen, anti-androgens, or progestogens.

The goal of denanderie is to reduce physical and psychological discomfort linked to androgen presence, such as facial hair growth, deepening of the voice, acne, or gender incongruence. For some individuals, this process is part of a broader transition journey, while for others, it may be a temporary or exploratory step. Denanderie is generally overseen by healthcare professionals, including endocrinologists or gender clinics, to ensure safety and monitor potential side effects, such as changes in mood, bone density, or lipid levels.

While denanderie can be life-affirming for many, it is not universally applicable or necessary for all transgender or gender-nonconforming individuals. Some may choose alternative paths, such as social transitioning or other forms of medical or non-medical support. The decision to pursue androgen suppression is highly personal and should be made in collaboration with trusted medical and mental health providers. Ethical and informed consent practices are essential to ensure autonomy and well-being throughout the process.