CF3CSR
CF3CSR, or trifluoromethylthio radical, is an organic free radical characterized by the chemical structure CF₃CS·, where a sulfur atom is bonded to a trifluoromethyl group (CF₃) and a carbon atom with an unpaired electron. This radical belongs to the broader class of sulfur-centered radicals and is notable for its high reactivity and stability compared to many other organic radicals.
The trifluoromethylthio radical plays a significant role in organic synthesis, particularly in fluorinated chemistry. Its presence
In mechanistic studies, CF₃CSR is often generated through the homolytic cleavage of precursors like trifluoromethylthio compounds
The radical’s stability is attributed to the electron-donating effect of sulfur and the electron-withdrawing nature of
Research into CF₃CSR continues to explore its applications in medicinal chemistry, materials science, and catalytic processes.