Biofilmdriven

Biofilmdriven is a term used to describe processes, outcomes, or phenomena that are primarily determined by the presence and activity of microbial biofilms—structured communities of microorganisms attached to surfaces and embedded in a self-produced extracellular matrix. Biofilmdriven systems differ from those governed by free-floating (planktonic) cells, because biofilms create persistent, heterogeneous environments that influence chemistry, physics, and biology at the system level.

Key features of biofilmdriven dynamics include the development of chemical and nutrient gradients, enhanced cooperation among community members, and increased resistance to environmental stresses. The extracellular polymeric substance matrix provides mechanical stability and protection, contributing to tolerance to antimicrobials and to fluctuations in flow, pH, and temperature. Quorum sensing and other cell–cell communication pathways coordinate behavior such as growth, detachment, and differentiation within the biofilm.

Contexts where biofilmdriven processes are important span natural, industrial, medical, and environmental settings. In nature, biofilms drive biogeochemical cycling and mineral transformations. In industry, they can cause fouling, corrosion (microbiologically influenced corrosion), and process inefficiencies, but can also enable beneficial operations in biofilm reactors and wastewater treatment. In medicine and dentistry, biofilms underlie device-associated infections and dental plaque formation.

Research and management of biofilmdriven phenomena aim to promote beneficial biofilms and suppress harmful ones, using approaches such as surface modification, flow control, and targeted disruption of the biofilm matrix or signaling networks.