ALDd
ALDd, also known as Adrenoleukodystrophy, is a rare genetic disorder that primarily affects males. It is caused by mutations in the ABCD1 gene, which is responsible for producing a protein involved in the metabolism of very-long-chain fatty acids. These fatty acids are essential for the proper functioning of the nervous system and adrenal glands. The disorder is characterized by a progressive accumulation of very-long-chain fatty acids in the brain and adrenal glands, leading to a variety of symptoms.
The most common form of ALDd is X-linked adrenoleukodystrophy (X-ALD), which is inherited in an X-linked recessive
The symptoms of ALDd can vary widely and may include progressive neurological deterioration, adrenal insufficiency, and