tumormiljøets
Tumormiljøet, often referred to as the tumor microenvironment (TME), is the complex ecosystem surrounding a tumor. It is not just composed of cancer cells but also includes a diverse array of non-cancerous cells, extracellular matrix, and signaling molecules. These components interact dynamically with the tumor cells, influencing tumor growth, progression, metastasis, and response to therapy.
Key cellular components of the TME include cancer-associated fibroblasts (CAFs), immune cells such as tumor-infiltrating lymphocytes
The extracellular matrix (ECM) within the TME, composed of proteins like collagen and fibronectin, provides structural
Understanding the intricate composition and interactions within the tumormiljøet is vital for developing effective cancer treatments.