transdérmicas
Transdermal patches, known in Spanish as “transdérmicas,” are medical devices designed to deliver a drug through the skin into the systemic circulation. The technology exploits the skin’s ability to act as a reservoir, allowing for controlled, sustained release of medication over periods ranging from several hours to weeks. Transdermal systems are composed of an adhesive backing, a drug-containing matrix or reservoir, and a rate-controlling membrane in some designs. The adhesive ensures intimate contact with the skin, while the matrix or reservoir holds the active pharmaceutical ingredient (API) and any excipients needed to modulate release.
The primary advantages of transdérmicas include improved patient adherence, avoidance of gastrointestinal degradation or first‑pass hepatic
Drug selection for transdermal delivery depends on physicochemical properties: low molecular weight (generally < 500 Da), moderate lipophilicity
Safety considerations involve skin irritation, allergic reactions, and potential for overdose if patches are applied improperly.