subtypessquamous
Subtypes of squamous cell carcinoma (SCC) describe variations in differentiation and morphology of squamous neoplasms, as well as their anatomical location. This includes patterns seen in tumors arising from keratinized skin versus non-keratinized mucosal surfaces.
In normal tissue, stratified squamous epithelium is keratinized on the skin, forming a cornified epidermal layer,
Within SCC, common subtypes include keratinizing (well-differentiated) SCC, characterized by keratin pearls and abundant keratin; non-keratinizing
These subtypes occur in multiple organs, including the skin, head and neck, esophagus, cervix, and lungs. Diagnosis
Prognosis and treatment vary by subtype and stage; management commonly includes surgical resection with or without