selectinemoleculen
Selectinmoleculen are a family of cell adhesion molecules that play a crucial role in the initial stages of inflammation and immune responses. They are transmembrane glycoproteins that mediate the attachment of circulating leukocytes to the endothelial cells lining blood vessels. This process is essential for leukocytes to migrate from the bloodstream into tissues where they can carry out their functions, such as fighting infection or repairing damaged tissue.
There are three main types of selectins: L-selectin, P-selectin, and E-selectin. L-selectin is primarily expressed on
The binding of selectins to their carbohydrate ligands on opposing cells is a relatively weak and transient