postinfusion

Postinfusion refers to the period after the completion of an infusion, most often an intravenous administration of fluids, medications, or nutrients. It is distinct from the infusion itself and from preinfusion assessment, and it encompasses observation, assessment of response, and management of any late-occurring effects.

In clinical practice, postinfusion monitoring typically includes vital signs, assessment for symptoms such as fever, chills, rash, dyspnea, hypotension, or edema, and observation for signs of infusion-related reactions or complications at the IV site. The observation window varies with the substance given and can range from minutes to several hours, with some therapies requiring longer follow-up for delayed effects.

Potential issues during the postinfusion period include late-onset infusion-related reactions, fluid overload, electrolyte disturbances, and localized problems such as extravasation or phlebitis. Management involves continued observation, symptom management, discontinuation or modification of therapy if needed, and communication with the supervising clinician for further evaluation or dose adjustment.

In pharmacokinetics and clinical research, postinfusion sampling may be used to measure drug concentrations after infusion to determine parameters such as peak concentration, half-life, and overall exposure. Documentation and clear communication are essential in postinfusion care, including recording the times, doses, fluids administered, patient status, and any adverse events.