polygenically
Polygenically refers to traits or conditions influenced by multiple genes rather than a single gene. Unlike monogenic disorders, which are caused by mutations in one specific gene, polygenic traits arise from the combined effects of various genetic variants across the genome. These traits often exhibit complex patterns of inheritance, where each contributing gene may have a small effect, and environmental factors can also play a significant role.
Polygenic inheritance is common in many human characteristics, including height, weight, skin color, and susceptibility to
The study of polygenic traits involves statistical methods to identify genetic associations, such as genome-wide association
Understanding polygenic inheritance is crucial in medicine, as it informs risk assessment, personalized treatment strategies, and