perfusionsCT
Perfusion CT, also known as CT perfusion imaging, is a dynamic imaging modality that assesses tissue perfusion by tracking intravenously injected iodinated contrast as it passes through the cerebral or other tissue vasculature. The technique uses rapid, repeated CT acquisitions after contrast injection to generate time-attenuation curves and parametric maps of perfusion.
In the brain, common parameters include cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time
Clinical use: In acute ischemic stroke, perfusion CT is used to extend the time window for reperfusion
Technical considerations: The protocol involves an IV contrast bolus and rapid CT scans over tens of seconds,
Limitations include variations in thresholds for core vs penumbra, potential underestimation of CBF in flow-limited tissue,
Research and guidelines: Perfusion CT findings are integrated into guideline recommendations for acute stroke management in