organonachipmodeller
Organonachipmodeller is a term used to describe the practice, software tools, and professionals involved in creating computational models of organ-on-a-chip systems. Organ-on-a-chip devices are microfluidic platforms that replicate key physiological functions of human organs by culturing living cells in networks of channels and porous membranes. The goal of organonachipmodelling is to simulate fluid flow, mass transport, cellular behavior, and tissue mechanics within these devices to understand function, optimize design, and predict responses to drugs or disease conditions.
Modelling approaches typically combine methods from computational fluid dynamics, finite element analysis, reaction-diffusion systems, and agent-based
Applications of organonachipmodellers include aiding drug discovery and toxicology assessments, investigating disease mechanisms in engineered tissue
Challenges include achieving accurate parameter estimation, validating models against experimental data, and bridging scales from microscale