odontoonychodermal
Odontoonychodermal dysplasia, also known as odonto-onycho-dermal dysplasia (OODD), is a rare autosomal recessive ectodermal dysplasia characterized by abnormal development of ectodermal structures, particularly teeth, nails, and skin. The condition reflects disruption of pathways that govern ectodermal differentiation and morphogenesis.
Clinical features commonly involve dental anomalies such as hypodontia or anodontia (missing teeth), irregular tooth shapes
Genetically, most cases are inherited in an autosomal recessive pattern. The disorder has been associated with
Diagnosis relies on clinical recognition of the characteristic triad (dental, nail, and skin findings) supported by
Management is multidisciplinary, focusing on functional and cosmetic rehabilitation. Dental care may include prosthetic replacements and