nitrosamiine
Nitrosamines are a class of organic compounds characterized by the presence of a nitroso group bonded to a nitrogen atom of an amine, giving the general structure R2N–N(=O)–R'. They are commonly referred to as N-nitrosamines, with notable examples such as N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA).
Formation and occurrence: Nitrosamines form when nitrosating agents, such as nitrous acid or nitrites in acidic
Properties and examples: Nitrosamines vary in volatility and polarity. NDMA and NDEA are among the most studied
Health effects and regulation: Nitrosamines are of concern because they are carcinogenic in animals and are
Detection and mitigation: Analytical methods such as gas chromatography–mass spectrometry and liquid chromatography–mass spectrometry are used