nefrotoksilisust
Nefrotoksilisus, or nephrotoxicity, refers to damage to the kidneys caused by exposure to toxic substances. The condition can result from drugs, chemicals, environmental toxins, or medical procedures. In clinical practice, nephrotoxicity is a major concern because it can impair renal function, lead to acute kidney injury, or worsen chronic kidney disease.
The mechanisms of kidney injury vary according to the agent involved. Many nephrotoxic drugs accumulate within
Early signs of nephrotoxicity include reduced urine output, hematuria, or proteinuria. More advanced injury may present
Management focuses on eliminating the offending agent, optimizing hydration, and providing supportive care. Renal replacement therapy
Nefrotoksilusust is a growing public health concern, especially with increased use of novel pharmaceuticals and imaging