microkorrels
Microkorrels are submicroscopic particles, typically ranging in size from 10 to 200 nanometers, that exhibit unique optical and mechanical properties due to their quantum confinement effects. They are distinguished from other nanoscale materials by their core–shell architecture, where a semiconductor or metallic core is followed by a ligand or polymer shell that provides stability, biocompatibility, and functionalization capability. The core material is commonly cadmium selenide or zinc sulfide, while surface ligands may include thiolates, phosphates, or polyethylene glycol.
The synthesis of microkorrels generally involves colloidal chemistry techniques such as hot‑injection or solvothermal methods. Reaction
In biomedical research, microkorrels act as fluorescent probes, drug carriers, and imaging agents. Their narrow emission
Safety considerations are critical; cadmium‑based microkorrels pose toxicity risks, prompting research into lead‑free alternatives. Regulatory frameworks