makrofaj
Makrofaj, or macrophages, are large phagocytic cells of the immune system. They are key players in the innate immune response and are found in virtually all body tissues as tissue-resident macrophages. They originate from hematopoietic stem cells in the bone marrow, with circulating monocytes that can differentiate into macrophages upon entering tissues. Some tissue macrophage populations originate embryonically and persist independently of monocytes.
Macrophages perform a range of essential functions. They phagocytose and destroy microorganisms, dead cells, and cellular
Macrophages are widespread and highly specialized in different tissues. Examples include Kupffer cells in the liver,
Macrophages contribute to both health and disease. While essential for host defense and tissue maintenance, dysregulated