lungetransplantation
Lung transplantation is a surgical procedure in which a diseased lung is replaced with a healthy donor lung, usually from a deceased donor. The operation is considered for patients with end-stage pulmonary disease when other treatments have not provided adequate improvement. Transplants can be single-lung or double-lung; in some centers, living-donor lobar transplants are performed in selected cases.
Indications include chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, cystic fibrosis, pulmonary arterial hypertension, sarcoidosis, and
Donor lungs are obtained from brain-dead donors and must be ABO compatible and appropriately sized for the
During surgery, the diseased lungs are removed and the donor lungs are connected to the recipient’s airways
Risks include primary graft dysfunction, infection, acute rejection, chronic rejection (bronchiolitis obliterans syndrome), anastomotic problems, bleeding,
Follow-up is lifelong and includes regular monitoring, vaccination, pulmonary rehabilitation, and adherence to immunosuppressive therapy.