letrosole

Letrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors. These drugs work by blocking the action of an enzyme called aromatase, which is responsible for converting androgens into estrogen in the body. Since many breast cancers are fueled by estrogen, reducing estrogen levels can slow or stop the growth of these tumors.

Beyond breast cancer treatment, letrozole is also used off-label to induce ovulation in women with infertility issues, particularly those with polycystic ovary syndrome (PCOS). By suppressing estrogen, it can lead to an increase in follicle-stimulating hormone (FSH), which in turn stimulates the development of ovarian follicles.

The medication is typically taken orally as a tablet once a day. Like all medications, letrozole can have side effects. Common side effects include hot flashes, joint pain, fatigue, and nausea. Less common but more serious side effects can include bone thinning (osteoporosis), increased risk of cardiovascular events, and changes in mood. It is crucial for patients to discuss the potential benefits and risks of letrozole with their healthcare provider to determine if it is the appropriate treatment for their condition. Regular monitoring of bone density and other health indicators is often recommended during treatment.