kvantilenormalisering
Kvantilenormalisierung, also known as quantile normalization, is a statistical technique used primarily in the preprocessing of high-throughput data, such as gene expression microarrays and RNA sequencing. Its main purpose is to make the distributions of data across multiple samples comparable by adjusting their statistical properties to a common reference distribution.
The method operates by ranking the data points within each sample and then replacing these original values
Kvantilenormalisierung is particularly popular in bioinformatics and systems biology because it facilitates the comparison of gene
While effective in standardizing data, kvantilenormalisierung has limitations; it can mask genuine biological variation if the
The technique was introduced in the early 2000s and has since become a standard preprocessing step for
In summary, kvantilenormalisierung is a method that aligns sample data distributions to improve comparability and reduce